[In vitro activity of trovafloxacin in 238 respiratory pathogens]

The in vitro activity of trovafloxacin against 238 clinical isolates obtained from respiratory specimens were compared with ciprofloxacin. Fifty-four Haemophilus influenzae, 58 Streptococcus pneumoniae, 40 Moraxella catarrhalis, 21 Streptococcus pyogenes, 25 Klebsiella pneumoniae and 40 Staphylococcus aureus (21 methicillin resistant and 19 methicillin susceptible) were studied. The MIC was determined following NCCLS recommendations. Ciprofloxacin and trovafloxacin MIC90 was 0.016 mg/l and 0.016 mg/l for H. influenzae, 4 mg/l and 0. 25 mg/l for S. pneumoniae,