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Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
09:12

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae

Published on: January 17, 2014

[Resistant Streptococcus pneumoniae]

M Martínez Hornos1, M Fernández López, E Becerril Carral

  • 1Sección de Infectología Pediátrica y Departamento de Microbiología del H.U. Virgen del Rocío, Avda. Manuel Siurot s/n, 41013 Sevilla.

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|October 31, 1998
PubMed

Insights

Streptococcus pneumoniae resistance is rising in children, with increased cefotaxime resistance linked to penicillin resistance. Vancomycin remains effective, but other antibiotics show significant resistance.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pediatrics

Context:

  • Streptococcus pneumoniae is a leading cause of pediatric infections.
  • Recent years have seen a concerning increase in antibiotic resistance.
  • Third-generation cephalosporins are increasingly ineffective.

Purpose:

  • To review Streptococcus pneumoniae strains from pediatric patients.
  • To analyze the incidence of resistance to cefotaxime and penicillin.
  • To assess the resistance patterns of penicillin-resistant strains to other antibiotics.

Summary:

  • A rise in cefotaxime resistance was observed in pediatric Streptococcus pneumoniae isolates.
  • This cefotaxime resistance was significantly correlated with penicillin resistance.
  • Penicillin-resistant strains showed high resistance to erythromycin, chloramphenicol, and cotrimoxazole.
  • Vancomycin demonstrated 100% susceptibility in these resistant strains.

Impact:

  • Highlights the growing threat of multidrug-resistant Streptococcus pneumoniae in children.
  • Informs clinical decisions regarding antibiotic selection for pediatric infections.
  • Underscores the need for continued surveillance and development of new antimicrobial agents.

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