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Related Experiment Videos

Eosinophilic gastroenteritis--an Indian experience

S Venkataraman1, B S Ramakrishna, M Mathan

  • 1Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|October 31, 1998
PubMed
Summary
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Eosinophilic gastroenteritis is a rare condition affecting young adults, often presenting with abdominal pain and vomiting. Peripheral eosinophilia and biopsy confirmed the diagnosis, with most patients responding to prednisolone treatment.

Area of Science:

  • Gastroenterology
  • Pathology
  • Immunology

Background:

  • Eosinophilic gastroenteritis is an uncommon gastrointestinal disorder.
  • Characterized by eosinophilic infiltration of the gastrointestinal tract.
  • Presents with diverse symptoms, making diagnosis challenging.

Observation:

  • A retrospective analysis of 7 patients (6 male, mean age 32) with eosinophilic gastroenteritis over 10 years.
  • Common symptoms included abdominal pain, vomiting, weight loss, diarrhea, and abdominal distension.
  • All patients exhibited peripheral eosinophilia.

Findings:

  • Diagnosis confirmed via duodenal, cecal, or jejunal biopsy.
  • Three disease subtypes identified: mucosal (Type I), muscular (Type II), and submucosal (Type III).

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  • One patient with Type II disease achieved remission with surgical resection; six patients responded to prednisolone.

    • Implications:

    • Highlights the varied clinical presentations of eosinophilic gastroenteritis.
    • Emphasizes the diagnostic role of biopsy and peripheral eosinophilia.
    • Suggests prednisolone as a primary treatment modality for eosinophilic gastroenteritis.