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Related Experiment Videos

Lymphedema: classification, diagnosis and therapy

A Szuba1, S G Rockson

  • 1Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk Cardiovascular Research Center, CA 94305, USA.

Vascular Medicine (London, England)
|October 31, 1998
PubMed
Summary

Lymphedema diagnosis relies on clinical signs, with imaging aiding early detection. Treatment primarily involves conservative compression therapies, while surgical options remain experimental for this chronic condition.

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Area of Science:

  • Medicine
  • Vascular Medicine
  • Medical Diagnostics

Background:

  • Lymphedema is a chronic condition characterized by fluid accumulation.
  • It can be primary or secondary to other diseases or surgery.
  • Filariasis and postsurgical complications are common causes worldwide and in the USA, respectively.

Purpose of the Study:

  • To review the diagnostic features, pathophysiology, and therapies for lymphedema.
  • To highlight the role of ancillary tests in diagnosis.
  • To discuss current and experimental treatment modalities.

Main Methods:

  • Review of diagnostic modalities including isotopic lymphoscintigraphy, lymphography, MRI, CT, and ultrasonography.
  • Discussion of primary and secondary causes of lymphedema.

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  • Overview of conservative and surgical treatment options.

    • Main Results:

    • Lymphedema diagnosis is often clinical but may require imaging.
    • Secondary lymphedema is more common, with filariasis and postsurgical causes prevalent globally and in the USA.
    • Conservative compression therapy is the mainstay of treatment.

    Conclusions:

    • Early diagnosis of lymphedema can be supported by various imaging techniques.
    • While conservative management is standard, lymphatic microsurgery shows promise but is still experimental.
    • Understanding pathophysiology is key to managing complications like cellulitis and lymphangiosarcoma.