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In Vivo Immunofluorescence Localization for Assessment of Therapeutic and Diagnostic Antibody Biodistribution in Cancer Research
Published on: September 16, 2019
[Differences in the levels of serum immunoglobulins in various cancer patients]
IgG and IgM were purified from human peripheral blood sera and IgA from human colostrum. A method is established to measure the Ig classes quantitatively which is a modification of Mancini's radialimmundiffusion technique. Three Ig clases were detected from 136 cancer patients and compared with 34 healthy controls. In sarcoma there was an increase in the 3 classes of Ig in serum. These differences were also significant in patients with bone tumors. A raised level of three classes of Ig was seen.
IgG and IgM were purified from human peripheral blood sera and IgA from human colostrum. A method is established to measure the Ig classes quantitatively which is a modification of Mancini's radialimmundiffusion technique. Three Ig clases were detected from 136 cancer patients and compared with 34 healthy controls. In sarcoma there was an increase in the 3 classes of Ig in serum. These differences were also significant in patients with bone tumors. A raised level of three classes of Ig was seen.
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