Related Experiment Videos
Analysis of chromosome 6 markers in eight Utah schizophrenia pedigrees
1Department of Psychiatry, University of Utah School of Medicine, Salt Lake City 84132, USA.
Psychiatric Genetics
|November 4, 1998
Abstract:
Eight multiplex Utah schizophrenia pedigrees were screened for linkage by applying a non-parametric linkage program, GENEHUNTER, using 30 chromosome 6 DNA markers. The overall maximum NPL score of the combined pedigrees was 1.50 (P = 0.079) at marker D6s281, located near the q terminus. The highest overall maximum NPL score for an individual pedigree was 2.81 (P = 0.043). In the chromosome 6p region, where numerous positive findings have been reported, we obtained no positive results.