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Primary renal mucormycosis
N Lussier1, M Laverdière, K Weiss
1Department of Microbiology-Infectious Diseases, Hôpital Maison-neuve-Rosemont, Université de Montréal, Québec, Canada.
Abstract:
Primary renal mucormycosis is a rare infection capable of acute illness with sepsis. Few cases have been reported. We report a case of an acute primary renal mucormycosis and review the published reports. The incidence of primary renal mucormycosis has risen in recent years. The most frequently reported underlying predisposing disorders are human immunodeficiency virus infection, intravenous drug abuse, and diabetes mellitus. Primary renal mucormycosis should be suspected in patients with an immunocompromising illness or particular risk factors, when persistent flank pain and fever with sterile urine not responding to appropriate antibiotics are associated with enlarged heterogeneous kidneys.
Insights
Primary renal mucormycosis is a rare but serious kidney infection. Suspect this fungal infection in immunocompromised patients with persistent flank pain, fever, and sterile urine unresponsive to antibiotics.
Area of Science:
- Mycology
- Infectious Diseases
- Nephrology
Background:
- Primary renal mucormycosis is a rare fungal infection.
- It can lead to acute illness and sepsis.
- Few cases have been previously reported.
Observation:
- This report details a case of acute primary renal mucormycosis.
- A review of published literature was conducted.
- The incidence of this condition appears to be increasing.
Findings:
- Common predisposing factors include human immunodeficiency virus infection, intravenous drug abuse, and diabetes mellitus.
- Clinical presentation involves persistent flank pain and fever with sterile urine.
- Enlarged, heterogeneous kidneys on imaging are characteristic.
Implications:
- Early suspicion is crucial for timely diagnosis and treatment.
- Consider primary renal mucormycosis in at-risk patients with unexplained symptoms.
- Prompt management can prevent severe complications like sepsis.