Design and synthesis of a transition state analogue for the Diels-Alder reaction

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Updated: Oct 27, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
12:07

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes

Published on: April 1, 2013

P S Arora1, Q N Van, M Famulok

  • 1Department of Chemistry, University of California-Irvine 92697-2025, USA.

Bioorganic & Medicinal Chemistry
|November 5, 1998
PubMed

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Characteristics of the diene
Conformation
The simplest example of a diene is 1,3-butadiene, an acyclic conjugated π system. At room temperature, the molecule exists as a mixture of s-cis and s-trans conformers by virtue of rotation around the carbon–carbon single bond. Although the s-trans isomer is more stable, the...
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