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Single-read sequence tags of a limited number of genomic DNA fragments provide an inexpensive tool for comparative
K Hartung1, D Frishman, A Hinnen
1Hans-Knöll-Institut für Naturstoff-Forschung, Jena, Germany.
Yeast (Chichester, England)
|November 5, 1998
Abstract:
Single-read sequences from both ends of 415 3-kb average size genomic DNA fragments of Candida albicans were compared with the complete sequence data of Saccharomyces cerevisiae. Comparison at the protein level, translated DNA against protein sequences, revealed 138 sequence tags with clear similarity to S. cerevisiae proteins or open reading frames. One case of synteny was found for the open reading frames of RAD16 and LYS2, which are adjacent to each other in S. cerevisiae and C. albicans.