Related Experiment Videos
Hydroa vacciniforme with ocular involvement
W Wisuthsarewong1, V Leenutaphong, S Viravan
1Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Summary
Hydroa vacciniforme, a skin condition, can affect the eyes, causing uveitis and corneal issues. Protective sunglasses can prevent eye symptoms, even if skin lesions reappear.
Area of Science:
- Ophthalmology
- Dermatology
- Photobiology
Background:
- Hydroa vacciniforme is a rare, recurrent, and severe photosensitive disorder.
- Ocular manifestations in hydroa vacciniforme are not uncommon but require specific awareness.
Observation:
- A pediatric case of hydroa vacciniforme presented with recurrent anterior uveitis, corneal clouding, and stellate keratic precipitates.
- Skin lesions were reproducible with UVA phototesting, accompanied by systemic symptoms like fever and malaise.
- UVB phototesting did not reproduce the skin lesions.
Findings:
- The patient's eye symptoms were alleviated by wearing sunglasses, despite ongoing skin lesions.
- UVA radiation was identified as the likely trigger for both skin and systemic symptoms.
- This case highlights the significant ocular involvement associated with hydroa vacciniforme.
Implications:
- Ophthalmologists and dermatologists should consider eye involvement in hydroa vacciniforme diagnoses.
- Patients with hydroa vacciniforme, especially those with ocular symptoms, should be advised to use protective eyewear.
- Further research into the specific photobiology of hydroa vacciniforme may elucidate underlying mechanisms and improve patient management.