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Related Experiment Videos

Hydroa vacciniforme with ocular involvement

W Wisuthsarewong1, V Leenutaphong, S Viravan

  • 1Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|November 6, 1998
PubMed
Summary

Hydroa vacciniforme, a skin condition, can affect the eyes, causing uveitis and corneal issues. Protective sunglasses can prevent eye symptoms, even if skin lesions reappear.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Photobiology

Background:

  • Hydroa vacciniforme is a rare, recurrent, and severe photosensitive disorder.
  • Ocular manifestations in hydroa vacciniforme are not uncommon but require specific awareness.

Observation:

  • A pediatric case of hydroa vacciniforme presented with recurrent anterior uveitis, corneal clouding, and stellate keratic precipitates.
  • Skin lesions were reproducible with UVA phototesting, accompanied by systemic symptoms like fever and malaise.
  • UVB phototesting did not reproduce the skin lesions.

Findings:

  • The patient's eye symptoms were alleviated by wearing sunglasses, despite ongoing skin lesions.
  • UVA radiation was identified as the likely trigger for both skin and systemic symptoms.

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  • This case highlights the significant ocular involvement associated with hydroa vacciniforme.

    • Implications:

    • Ophthalmologists and dermatologists should consider eye involvement in hydroa vacciniforme diagnoses.
    • Patients with hydroa vacciniforme, especially those with ocular symptoms, should be advised to use protective eyewear.
    • Further research into the specific photobiology of hydroa vacciniforme may elucidate underlying mechanisms and improve patient management.