Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Strong gradients for spatially resolved diffusion measurements

J E Snaar1, P Robyr, R Bowtell

  • 1Department of Physics, University of Nottingham, University Park, UK.

Magnetic Resonance Imaging
|November 6, 1998
PubMed
Summary

Researchers developed a new multilayer gradient coil for stronger magnetic fields. This coil enabled monitoring water diffusion in Nylon 6.6, revealing concentration-dependent properties.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bespoke magnetic field design for a magnetically shielded cold atom interferometer.

Scientific reports·2022
Same author

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI.

NeuroImage·2018
Same author

Global signal modulation of single-trial fMRI response variability: Effect on positive vs negative BOLD response relationship.

NeuroImage·2016
Same author

Investigating intrinsic connectivity networks using simultaneous BOLD and CBF measurements.

NeuroImage·2014
Same author

Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG-BOLD-CBF study in humans.

NeuroImage·2014
Same author

Abstracts of Presentations at the International Conference on Basic and Clinical Multimodal Imaging (BaCI), a Joint Conference of the International Society for Neuroimaging in Psychiatry (ISNIP), the International Society for Functional Source Imaging (ISFSI), the International Society for Bioelectromagnetism (ISBEM), the International Society for Brain Electromagnetic Topography (ISBET), and the EEG and Clinical Neuroscience Society (ECNS), in Geneva, Switzerland, September 5-8, 2013.

Clinical EEG and neuroscience·2013

Area of Science:

  • Materials Science
  • Physical Chemistry
  • Magnetic Resonance Imaging

Background:

  • Designing strong gradient coils for nuclear magnetic resonance (NMR) applications is challenging due to power dissipation and resistance constraints.
  • Monitoring low diffusion coefficients ( < 10(-13) m2s-1) and short relaxation times ( < 1 ms) in materials like Nylon 6.6 requires advanced NMR techniques.

Purpose of the Study:

  • To develop a novel multilayer gradient coil design for enhanced strength and efficiency.
  • To investigate the diffusion of water in Nylon 6.6 using the new gradient coil system.
  • To characterize the concentration dependence of water's T2 relaxation time and self-diffusion coefficient.

Main Methods:

  • Development of a multilayer gradient coil with specific efficiency (1.73 Tm-1A-1), inductance (49 μH), and resistance (1.8 Ω).

Related Experiment Videos

  • Design of a z-gradient coil accommodating 5-mm NMR tubes for vertically mounted samples.
  • Utilizing the gradient coil to monitor water diffusion in Nylon 6.6 at room temperature during desorption.

    • Main Results:

    • The designed gradient coil achieved a significant efficiency and a homogeneous volume suitable for small sample analysis.
    • Measurements revealed a strong concentration dependence of the T2 relaxation time and self-diffusion coefficient of absorbed water in Nylon 6.6.
    • Observed concentration profiles were consistent with a Fickian diffusion model with a concentration-dependent diffusion coefficient.

    Conclusions:

    • The multilayer gradient coil design offers a viable method for producing strong gradient coils with manageable power requirements.
    • The study successfully monitored challenging water diffusion in Nylon 6.6, providing insights into its concentration-dependent transport properties.
    • Results support a Fickian diffusion model and highlight the utility of advanced NMR gradient coils for materials science research.