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Updated: Jul 26, 2026
Localization of the Locus Coeruleus in the Mouse Brain
Published on: March 7, 2019
Quantitative trait loci implicated in corpus callosum midsagittal area in mice
I L Roy1, F Perez-Diaz, P Roubertoux
1UPR CNRS 9074, Génétique, Neurogénétique, Comportement, Institut de Transgénose, CNRS, 3 B Rue de la Ferollerie, 45071, Orléans Cedex 02, France.
Abstract:
The midsagittal area of the corpus callosum expressed as the percentage of the hemispheric surface is smaller in the NZB/BlNJ than in the C57BL/6By inbred strain of mice. We performed a QTL mapping analysis using 284 F2s. Two loci linked to this measure were found: the CCrSQTL1 and CCrSQTL2 at 87 and 67 centiMorgans from the centromere on chromosomes 1 and 4 respectively. The two loci interacted significantly. The total source of genetic variation contributed to 25% of the observed variance.
