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Updated: Jul 30, 2026
12:03
Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
[Postpartum myocardial infarction induced by Parlodel]
Archives Des Maladies Du Coeur Et Des Vaisseaux
|November 7, 1998
Summary
Postpartum myocardial infarction occurred in a woman treated with Parlodel to inhibit lactation. This event was linked to drug-induced vasospasm, smoking, and postpartum arterial changes, highlighting the need for smoking cessation.
Area of Science:
- Cardiology
- Obstetrics
- Pharmacology
Background:
- Postpartum period presents unique cardiovascular risks.
- Medications for lactation inhibition require careful consideration.
- Systemic embolism can be a precursor to serious cardiac events.
Observation:
- A 28-year-old woman experienced antero-septoapical myocardial infarction postpartum.
- The infarction occurred after treatment with Parlodel (bromocriptine) for lactation inhibition.
- Diagnosis was confirmed by ECG and echocardiography following a systemic embolism.
Findings:
- Coronary angiography was normal one month postpartum.
- Methergin test was negative, ruling out ergotism.
- The myocardial infarction mechanism involved iatrogenic vasospasm, smoking, and postpartum arterial hyperactivity.
Implications:
- This case suggests a potential link between Parlodel, smoking, and postpartum myocardial infarction.
- Preventive measures, including smoking cessation, are crucial for women using lactation inhibitors postpartum.
- Further research into the cardiovascular risks of lactation inhibition pharmacotherapy is warranted.
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