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Antidepressants and posttraumatic stress disorder

J K Meek1, A Kablinger

  • 1Outpatient Psychiatry Clinic, Louisiana State University Medical Center, Shreveport, USA.

The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
|November 7, 1998
PubMed
Summary

Antidepressants effectively manage symptoms of posttraumatic stress disorder (PTSD). This review covers tricyclic antidepressants, monoamine oxidase inhibitors, and serotonin-selective reuptake inhibitors, confirming their therapeutic role.

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Area of Science:

  • Psychiatry
  • Pharmacology

Background:

  • Posttraumatic stress disorder (PTSD) significantly impacts individuals' mental health.
  • Symptomatic treatment is crucial for managing PTSD.
  • Antidepressants are a key therapeutic class explored for PTSD.

Purpose of the Study:

  • To review current literature on antidepressant use for PTSD symptoms.
  • To evaluate the effectiveness of various antidepressant classes in PTSD treatment.

Main Methods:

  • Literature review of recent data.
  • Analysis of studies on tricyclic antidepressants (TCAs).
  • Examination of monoamine oxidase inhibitors (MAOIs) and serotonin-selective reuptake inhibitors (SSRIs) in PTSD.

Main Results:

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  • TCAs, MAOIs, and SSRIs show effectiveness in treating PTSD symptoms.
  • Recent data supports the utility of these antidepressant classes.
  • Consistent findings across reviewed literature indicate antidepressant efficacy.

Conclusions:

  • Antidepressants are effective in controlling PTSD symptoms.
  • The reviewed antidepressant classes offer viable treatment options for PTSD.
  • Further research may refine antidepressant selection for optimal PTSD management.