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No difference in survival between sporadic, familial and hereditary prostate cancer
H Grönberg1, L Damber, B Tavelin
1Department of Oncology, Umeå Universitet, Sweden.
Objective:
To estimate the survival of men with familial prostate cancer and compare them with prostate cancer cases unselected for family history.
Patients And Methods:
The overall and prostate cancer-specific survival was calculated in two large (249 and 304 men, respectively) population-based cohorts of men with familial prostate cancer. The tumour grade at diagnosis was also obtained in one of the cohorts.
Results:
There were no significant differences in either overall or prostate cancer-specific survival between familial and sporadic cases. The spectrum of tumour grades at diagnosis in familial cases did not differ from that in a population with prostate cancer unselected for family history.
Conclusion:
No differences in treatment between men with or without a positive family history of prostate cancer are justified, based on the result from this study.