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Quantitative detection of hepatitis B virus DNA with a new PCR assay
H H Kessler1, K Pierer, B I Santner
1Institute of Hygiene, Karl-Franzens-University, Graz, Austria. harald.kessler@kfunigraz.ac.at
Clinical Chemistry and Laboratory Medicine
|November 7, 1998
Abstract:
The Amplicor HBV Monitor Test for quantitative detection of serum hepatitis B virus (HBV) DNA has recently been introduced. This assay is based on PCR and a non-radioactive hybridization and detection system on microwell plates. Evaluation in a routine diagnostic laboratory showed excellent sensitivity and adequate reproducibility; however, a more automated format would be desirable. The Amplicor HBV Monitor Test is useful for recognizing those patients who might benefit from antiviral treatment and for evaluation of the efficacy of anti-hepatitis B virus treatment.