Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aspergillus flavus keratitis

G N Chin, N L Goodman

    Annals of Ophthalmology
    |April 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    This case report details a rare and destructive Aspergillus flavus corneal ulcer resistant to standard antifungal treatments. Prompt surgical intervention is crucial for invasive fungal keratitis unresponsive to medication.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Treatment of vernal keratoconjunctivitis with topical cromolyn sodium.

    Journal of pediatric ophthalmology and strabismus·2014
    Same author

    Lag screw fixation of dorsal cortical stress fractures of the third metacarpal bone in 116 racehorses.

    Equine veterinary journal·2010
    Same author

    Endophthalmitis and lumbar diskitis due to Acremonium falciforme in a splenectomized patient.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·1997
    Same author

    New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis.

    The Annals of pharmacotherapy·1994
    Same author

    Peritonitis due to Exophiala jeanselmei in a patient undergoing continuous ambulatory peritoneal dialysis.

    American journal of kidney diseases : the official journal of the National Kidney Foundation·1993
    Same author

    Lameness diagnosis and treatment in the quarter horse racehorse.

    The Veterinary clinics of North America. Equine practice·1990
    Same journal

    Ocular toxicity of systemic chemotherapy with megadoses of carmustine and mitomycin.

    Annals of ophthalmology·1994
    Same journal

    Congenital intrastromal epithelial cyst of the iris.

    Annals of ophthalmology·1994
    Same journal

    Diagnosis and treatment of orbital hemorrhagic lesions.

    Annals of ophthalmology·1994
    Same journal

    Clinical features of toxoplasmic retinochoroiditis in patients with acquired immunodeficiency syndrome.

    Annals of ophthalmology·1994
    Same journal

    The closed chamber slipping suture technique for iris repair.

    Annals of ophthalmology·1994
    Same journal

    The effect of gravity on the amplitude of accommodation.

    Annals of ophthalmology·1994
    See all related articles

    Area of Science:

    • Ophthalmology
    • Mycology
    • Infectious Diseases

    Background:

    • Fungal keratitis, particularly from Aspergillus flavus, is uncommon but can lead to severe corneal damage.
    • Standard antifungal agents like amphotericin B, pimaricin, and clotrimazole may not always be effective.

    Observation:

    • A case of Aspergillus flavus corneal ulcer is presented.
    • The infection proved refractory to multiple topical and systemic antifungal therapies.
    • The affected eye progressed to phthisis bulbi, indicating complete loss of ocular function.

    Findings:

    • Aspergillus flavus can cause destructive corneal ulcers resistant to conventional antifungal treatments.
    • Sensitivity testing of the isolated fungus is essential for guiding effective therapy.

    Related Experiment Videos

  • Late-stage or deep stromal infections may necessitate aggressive surgical management.

    • Implications:

    • Early diagnosis and appropriate antifungal sensitivity testing are vital for managing fungal keratitis.
    • Prompt surgical intervention, including excisional keratoplasty, is indicated for treatment-resistant or invasive fungal corneal infections.
    • Aggressive management strategies are required to prevent vision loss in severe cases of fungal keratitis.