Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reaction time responding in rats

A Blokland1

  • 1Department of Psychology, University of Maastricht, The Netherlands.

Neuroscience and Biobehavioral Reviews
|November 11, 1998
PubMed
Summary
This summary is machine-generated.

Reaction time tests in rats offer valuable insights into brain-behavior relationships, particularly for motor functions and aging. Methodological considerations are crucial for validly assessing reaction time in rats for cognitive studies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

No interaction between rivastigmine and citalopram on memory and novelty processing in healthy human volunteers.

Journal of psychopharmacology (Oxford, England)·2018
Same author

The mediating role of phosphodiesterase type 4 in the dopaminergic modulation of motor impulsivity.

Behavioural brain research·2018
Same author

Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: Clinical overview and translational considerations.

Neuroscience and biobehavioral reviews·2018
Same author

Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults.

Neuropharmacology·2017
Same author

Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata.

Brain structure & function·2017
Same author

Role of acetylcholine and serotonin in novelty processing using an oddball paradigm.

Behavioural brain research·2017
Same journal

Meaning in life and biological functioning: A multisystem synthesis and agenda for future research.

Neuroscience and biobehavioral reviews·2026
Same journal

Beyond Diagnosis: Why and How Virtual Reality Should be Used in Research on Neurodevelopmental Conditions?

Neuroscience and biobehavioral reviews·2026
Same journal

What eye-movements tell us about Disorders of Consciousness?

Neuroscience and biobehavioral reviews·2026
Same journal

Systematic Review of Tactile-Based Interventions Combined with Multisensory Stimulation Protocols in the Rehabilitation of Patients with Disorders of Consciousness.

Neuroscience and biobehavioral reviews·2026
Same journal

Exploring the prognostic value of resting state brain activity in Disorders of Consciousness: A coordinate-based meta-analysis.

Neuroscience and biobehavioral reviews·2026
Same journal

From microstates to macroscales: A critical review of maximum entropy modeling and energy landscape analysis in functional MRI.

Neuroscience and biobehavioral reviews·2026
See all related articles

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Animal Behavior

Background:

  • Reaction time (RT) is a traditional measure in human information processing research.
  • In animal research, RT paradigms are primarily used to study the striatum's role in movement initiation and aging processes.

Purpose of the Study:

  • To explore the utility of reaction time measures in animal research for understanding brain-behavior relationships.
  • To discuss methodological constraints and potential applications of RT assessment in rats.

Main Methods:

  • Review of existing literature on reaction time studies in animal models.
  • Analysis of experimental data to exemplify methodological challenges in rat RT assessment.
  • Comparison of rat RT parameters with human data.

Related Experiment Videos

Main Results:

  • Reaction time studies in rats have elucidated the role of neurotransmitters (dopamine, glutamate, GABA) and brain structures (striatum, prefrontal cortex) in motor initiation.
  • Methodological constraints in rat RT assessment include controlling for behavioral variability and ensuring RT values are comparable to human ranges.
  • Despite challenges, reaction time can be validly assessed in rats.

Conclusions:

  • Reaction time is a powerful tool for studying brain-behavior relationships in animals.
  • RT assessment in rats can extend beyond motor functions to investigate cognitive processes due to its direct measure of information processing.
  • Utilizing RT in rat models offers a promising avenue for advancing our understanding of cognitive functions and their neural underpinnings.