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[SAPHO syndrome and aseptic osteitis]

A Cotten1, N Boutry, X Demondion

  • 1Service de Radiologie Ostéo-Articulaire, Hôpital Roger Salengro, Lille, France.

Annales De Radiologie
|January 1, 1997
PubMed
Summary

SAPHO syndrome links skin conditions like acne and palmoplantar pustulosis with aseptic skeletal lesions. This rare condition, characterized by inflammation and bone changes, requires increased awareness for accurate diagnosis and treatment.

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Area of Science:

  • Rheumatology
  • Dermatology
  • Orthopedics

Context:

  • SAPHO syndrome (Synovitis, Acne, Palmoplantar pustulosis, Hyperostosis, Osteitis) presents with aseptic skeletal lesions, sometimes without skin manifestations.
  • The anterior chest wall is a common site, exhibiting osteosclerosis, hyperostosis, and arthritis.

Purpose:

  • To describe the clinical and radiological manifestations of SAPHO syndrome.
  • To highlight the association between skin conditions and skeletal involvement.
  • To emphasize the importance of recognizing SAPHO syndrome for diagnosis and management.

Summary:

  • SAPHO syndrome encompasses a spectrum of findings including synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis.
  • Skeletal lesions can affect the chest wall, spine, sacroiliac joints, and long bones, showing osteosclerosis or osteolysis with periosteal reactions.
  • Peripheral arthritis may occur but joint destruction is uncommon.

Impact:

  • Increased awareness of SAPHO syndrome can lead to earlier and more accurate diagnoses.
  • Understanding the diverse manifestations aids in differentiating SAPHO from other spondylarthropathies.
  • This knowledge facilitates appropriate treatment strategies for patients with this rare condition.

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