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[1997 FIVNAT general balance]

A Bachelot¹, J L Pouly, A Devecchi

¹FIVNAT, Hôpital de Bicêtre, Le Kremlin Bicêtre.

Contraception, Fertilite, Sexualite (1992)

|November 12, 1998

Summary

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[Adverse obstetric and perinatal outcome with in vitro fertilization technology: A French nationwide population-based study].

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In 1997, French in vitro fertilization (IVF) data showed tubal and male factors as leading causes of infertility. High pregnancy rates were linked to GnRH agonist stimulation, with fewer embryos transferred per cycle.

Area of Science:

Reproductive Medicine and Endocrinology
In Vitro Fertilization (IVF) and Assisted Reproductive Technologies (ART)

Context:

The French National Register on in vitro fertilization (FIVNAT) collected data from 3,854 initiated cycles and 36,583 oocyte recoveries in 1997.
Analysis focused on conventional IVF and intracytoplasmic sperm injection (ICSI) cycles, identifying causes of infertility and treatment protocols.

Purpose:

To analyze the trends and outcomes of IVF and ICSI procedures in France for 1997.
To evaluate the effectiveness of different stimulation regimens and embryo transfer policies on pregnancy rates.

Summary:

Tubal factor infertility (49.7%) and male factor infertility (45%) were primary indications for conventional IVF.
Gonadotropin-releasing hormone (GnRH) agonist stimulation, particularly with a long blockage period (82.6%), was associated with higher pregnancy rates.

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The average number of transferred embryos decreased to 2.50, with fewer than 10% of transfers involving more than 3 embryos, correlating with lower pregnancy rates.

Impact:

Pregnancy rates per recovery (20.5%) and per transfer (26.0%) remained stable compared to 1996, indicating consistent ART effectiveness.
The data supports the trend towards single or dual embryo transfer and highlights the importance of GnRH agonist protocols in optimizing IVF outcomes.