Related Experiment Video
Updated: Aug 15, 2026
Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
[Primary angioplasty in acute myocardial infarct. A report on 304 consecutive patients]
J M García y Otero1, E Frutos Rangel, R García García
1Departamento de Cardiología, Hospital del Carmen, Guadalajara, Jalisco, México.
Insights
Primary percutaneous coronary angioplasty (PTCA) is a successful treatment for acute myocardial infarction, achieving high success rates and low mortality, even in high-risk patients. This study details a single-center experience with 304 patients.
Area of Science:
- Cardiology
- Interventional Cardiology
Context:
- Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide.
- Timely reperfusion therapy is critical for improving outcomes in AMI.
- Primary percutaneous coronary angioplasty (PTCA) is a key reperfusion strategy.
Purpose:
- To report the single-center experience with primary PTCA in 304 consecutive patients with AMI.
- To evaluate the procedural success and in-hospital outcomes of primary PTCA.
- To assess the safety and efficacy of primary PTCA in a real-world patient cohort.
Summary:
- The study included 304 AMI patients (67% male, mean age 69 years) treated with primary PTCA.
- Key findings include a mean onset-to-treatment time of 3.5 hours, 14% prior bypass surgery, 23% prior MI, and 11% in cardiogenic shock.
- Procedural success was 95% with an in-hospital mortality of 6.5%, demonstrating effectiveness even in high-risk subgroups.
Impact:
- Primary PTCA is confirmed as an effective reperfusion strategy for acute myocardial infarction.
- The findings support the use of primary PTCA in diverse patient populations, including those with high-risk features.
- This study contributes to the evidence base for primary PTCA, showing comparable success and complication rates to published data.
Abstract:
The purpose of this study is to describe a single-center experience in primary coronary angioplasty in 304 consecutive patients with acute myocardial infarction. Sixty-seven percent were men and 33% women, the mean age was 69 years. The time from onset to treatment was 3.5 hours, 14% had previous bypass surgery and 23% prior myocardial infarction, 11% arrived in cardiogenic shock. Coronary angiography showed multivessel disease in 56% of patients, 73% had TIMI 0-1 flow. Successful PTCA occurred in 95% and in hospital mortality was 6.5%. Primary coronary angioplasty is a successful reperfusion method in acute myocardial infarction and it is associated with low mortality even in high risk groups. The rates of success and major complications in this series are similar to other publications.
