Related Experiment Videos
[Treatment of mitochondrial diseases in childhood and adolescence]
M Castro-Gago1, M I Novo-Rodríguez, J Eirís-Puñal
1Departamento de Pediatría, Hospital General de Galicia, Complejo Hospitalario Universitario de Santiago de Compostela, Sergas, España. pdcastro@uscmail.usc.es
Revista De Neurologia
|November 12, 1998
Abstract:
The advances made in recent years in understanding this large group of disorders has led to the development of ways of approaching their treatment, although in most cases it is neither definitive nor curative. In this article we review current aspects of the treatment of defects: of substrate transport, substrate use, the Krebs cycle, the mitochondrial respiratory chain and oxidation-phosphorylation coupling. We conclude with comments on possible future treatment.