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Updated: Aug 8, 2026

Isolation and Transplantation of Different Aged Murine Thymic Grafts.
Published on: May 13, 2015
Graves' disease presenting as localized myxedema in a thigh donor graft site
S C Missner1, E W Ramsay, H E Houck
1University of Maryland School of Medicine, Baltimore Campus, Department of Dermatology, USA.
Abstract:
Pretibial myxedema, exophthalmus, and thyroid acropachy are the classic manifestations of Graves' Disease. However, myxedema in Graves' Disease can occur in locations other than the pretibial surfaces. Furthermore, with systemic symptoms, localized myxedema may occur at sites of trauma or scarring. We describe a patient with localized myxedema on the thigh at the site of a donor skin graft as the initial presentation of Graves' Disease.
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