[Multifactor analysis on proliferative retinopathy in elderly patients with type II diabetes]

To evaluate the importance of different risk factors and their mutual interactions in the occurrence of proliferative diabetic retinopathy (PDR) in the elderly patients with type II diabetes, an investigation was carried out on the relationship between PDR and various risk factors in 98 elderly cases of type II diabetes by way of stepwise regression analysis method. Results showed: (1) the average course of PDR was longer than that of diabetic patients without diabetic retinopathy (P < 0.01). Patients with PDR had higher values of BUN (P < 0.01), Cr(P < 0.05), GHbA1c(P < 0.01) and TC(P < 0.01) than those without retinopathy. Patients with PDR had higher coincidences of hypertension, coronary artery disease, proteinuria and urine microalbumin than those without retionpathy (P < 0.01) respectively, (2) multifactor analysis showed that BUN was one of the most important variables positively correlated with PDR, second to it in orders were the course of diabetes militus, GHbA1c, hypertention, proteinuria and urine microalbumin and TC.

To prevent the occurrence and progress of PDR in the elderly patients with type II diabetes, it is important not only to control blood sugar, but to control blood pressure and relieve renal damage.