Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Diet and antioxidant--a nutritional intervention study]

L He1, I Persson, R Rylander

  • 1Institute for Chemical Carcinogenesis, Guangzhou Medical College, PR. China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|November 13, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coprecipitation of Ce(III) oxide with UO<sub>2</sub>.

Journal of synchrotron radiation·2024
Same author

Ti <sub></sub>C <sub></sub> MXenes with fully saturated and thermally stable Cl terminations.

Nanoscale advances·2022
Same author

Quality Indicators of Nutritional Care Practice in Elderly Care.

The journal of nutrition, health & aging·2017
Same author

Risks of neurological and immune-related diseases, including narcolepsy, after vaccination with Pandemrix: a population- and registry-based cohort study with over 2 years of follow-up.

Journal of internal medicine·2016
Same author

Response to letter from Lars Andersson.

Journal of internal medicine·2016
Same author

Safety and efficacy of the combination of pegylated interferon-α2b and dasatinib in newly diagnosed chronic-phase chronic myeloid leukemia patients.

Leukemia·2016

Adding vegetables to the diet may boost cancer-protective antioxidant enzymes. While vitamin A and E levels didn't change, glutathione S-transferase (GST) gene expression increased in most participants.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Nutritional Science

Context:

  • Epidemiological studies suggest high vegetable intake correlates with reduced cancer risk.
  • Antioxidants are crucial in the body's defense against cancer.
  • Glutathione S-transferases (GSTs) are key enzymes protecting against oxidative damage.

Purpose:

  • To investigate the effect of increased vegetable intake on antioxidant enzyme activity.
  • To determine if dietary vegetables influence serum levels of retinol and alpha-tocopherol.
  • To assess the impact of vegetable consumption on glutathione S-transferase pi (GSTp) gene expression in lymphocytes.

Summary:

  • Serum retinol and alpha-tocopherol levels showed no significant change after dietary vegetable supplementation.

Related Experiment Videos

  • GST pi mRNA levels in lymphocytes increased in 80% of subjects following vegetable intake.
  • These findings suggest that non-vitamin A and E antioxidants in vegetables may induce GSTp gene transcription.

    • Impact:

    • Highlights potential mechanisms by which dietary vegetables contribute to cancer prevention.
    • Identifies specific antioxidant pathways that may be modulated by vegetable consumption.
    • Suggests further research into identifying active compounds in vegetables responsible for inducing GSTs.