Related Experiment Video
Updated: Oct 27, 2026

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors
Published on: June 7, 2016
Immunohistochemical localization of the angiotensin II type 1 receptor in human hypothalamus and brainstem
E E Benarroch1, A M Schmeichel
1Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. benarroch.eduardo@mayo.edu
Abstract:
We studied the distribution of the angiotensin II type 1 (AT-1) receptor using a polyclonal rabbit antibody in two human brains. AT-1 receptor immunoreactivity was detected in several hypothalamic nuclei, substantia nigra, locus coeruleus, nucleus tractus solitarius, ventrolateral medulla, pontine nuclei, and inferior olivary nucleus. This provides direct evidence of neuronal localization of the AT-1 receptor in autonomic and motor areas in human brain.
More Related Videos
08:34Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay
Published on: July 15, 2025
09:51Live Cell Imaging and 3D Analysis of Angiotensin Receptor Type 1a Trafficking in Transfected Human Embryonic Kidney Cells Using Confocal Microscopy
Published on: March 27, 2017