Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autism: the phenotype in relatives

A Bailey1, S Palferman, L Heavey

  • 1Medical Research Council Child Psychiatry Unit, Institute of Psychiatry, London, United Kingdom.

Journal of Autism and Developmental Disorders
|November 14, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chewing analysis of horses consuming bermudagrass hay in different styles of slow feeders as compared to loose hay.

Journal of equine veterinary science·2024
Same author

Treat Climate Change like the Public Health Emergency it is.

Irish medical journal·2023
Same author

Real-world clinical profile, treatment patterns and patient-reported outcomes in a subset of HR+/HER2- advanced breast cancer patients with poor prognostic factors: data from an international study.

ESMO open·2021
Same author

Staff and participant perceptions of optimal recruitment and retention strategies for biomedical cohort studies in the Caribbean.

Cancer causes & control : CCC·2021
Same author

Objective and subjective rapid frailty screening tools in people with HIV.

HIV medicine·2020
Same author

FAB: First UK feasibility trial of a future randomised controlled trial of Family focused treatment for Adolescents with Bipolar disorder.

International journal of bipolar disorders·2020
Same journal

Motor Competence and Physical Fitness in Children and Adolescents With ADHD: A Comparative Study with Typically Developing Peers.

Journal of autism and developmental disorders·2026
Same journal

Assessing Camouflaging in Adolescence: Psychometric Evaluation of the German Camouflaging Autistic Traits Questionnaire (CAT-Q/DE).

Journal of autism and developmental disorders·2026
Same journal

Behavior Regulation Abilities in Children With Prader-Willi Syndrome and Their Impact on Daily Life: At the Crossroads of Cognitive and Emotional Development.

Journal of autism and developmental disorders·2026
Same journal

The Role of Peer Victimisation and Parental Mental Health in Internalising Problems: Examining Bidirectional Relationships Across Childhood and Adolescence in Autistic Youth.

Journal of autism and developmental disorders·2026
Same journal

An Analysis of the Psychometric Properties of the Pediatric Inventory for Parents: Short Form Among Caregivers of Children Diagnosed With Autism Spectrum Disorder.

Journal of autism and developmental disorders·2026
Same journal

A Scoping Review on Positive Emotions and Affect in Autism.

Journal of autism and developmental disorders·2026
See all related articles

Genetic factors are key in autism development. Studies show relatives may exhibit milder autism-related traits, ranging from developmental disorders to personality differences, which require further clarification.

Area of Science:

  • Neurodevelopmental disorders
  • Genetics
  • Psychiatry

Background:

  • Idiopathic autism is widely accepted to have strong genetic underpinnings.
  • The presence and nature of milder, genetically related phenotypes in relatives of autistic individuals remain debated.
  • Understanding these milder phenotypes is crucial for a comprehensive view of autism's genetic architecture.

Purpose of the Study:

  • To review existing literature on milder phenotypes in relatives of individuals with autism.
  • To explore the spectrum of these related difficulties and their relationship to autism proper.
  • To outline challenges in defining and characterizing these milder phenotypes.

Main Methods:

  • Literature review of studies examining genetic influences and phenotypes in autism families.

Related Experiment Videos

  • Conceptual analysis of milder phenotypes reported in relatives.
  • Identification of issues in phenotype definition and relationship to autism.

    • Main Results:

    • Relatives of autistic individuals sometimes display difficulties conceptually linked to autistic behaviors.
    • These milder phenotypes vary in severity, from pervasive developmental disorders to single-domain impairments.
    • The spectrum may extend to related personality traits.

    Conclusions:

    • Evidence suggests genetically related milder phenotypes exist in relatives of autistic individuals.
    • Further research is needed to clarify the components and boundaries of these phenotypes.
    • Understanding the full spectrum of autism-related genetic effects is essential for genetic research and clinical practice.