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Pseudoappendicitis preceding infectious mononucleosis

P M Adcock1, H S Nagaraj, G S Marshall

  • 1Department of Pediatrics, University of Louisville School of Medicine, Kentucky, USA.

Pediatric Emergency Care
|November 14, 1998
PubMed
Summary
This summary is machine-generated.

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Abdominal pain in infectious mononucleosis can mimic appendicitis. Epstein-Barr virus (EBV) lymphoproliferation can cause localized pain before mononucleosis symptoms appear.

Area of Science:

  • Pediatric Infectious Diseases
  • Gastroenterology
  • Virology

Background:

  • Abdominal pain in infectious mononucleosis is often linked to organ enlargement.
  • Mesenteric adenitis is a common cause of abdominal pain in children and adolescents.

Observation:

  • A teenage girl presented with appendicitis-like symptoms.
  • Laparotomy revealed mesenteric adenitis, not appendicitis.
  • She later developed classic Epstein-Barr virus (EBV)-induced mononucleosis.

Findings:

  • EBV infection can cause significant lymphoproliferation.
  • This lymphoproliferation can lead to severe, localized abdominal pain.
  • The abdominal pain may precede other symptoms of mononucleosis.

Related Experiment Videos

Implications:

  • EBV infection should be considered in the differential diagnosis of acute abdominal pain in adolescents.
  • Localized lymphoproliferation can manifest as severe abdominal pain, mimicking surgical emergencies.
  • Early recognition of EBV-associated abdominal pain may prevent unnecessary surgical interventions.