Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transfusion-transmissible infections

H Vrielink1, H W Reesink

  • 1Red Cross Blood Bank Amsterdam, The Netherlands.

Current Opinion in Hematology
|November 14, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Findings in the Immuno-hematology workshop during the International Congress of the WAA 2024 in Indonesia.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2025
Same author

Analyses of registry data of patients with anti-GBM and antineutrophil cytoplasmatic antibody-associated (ANCA) vasculitis treated with or without therapeutic apheresis.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2021
Same author

Taking therapeutic apheresis services to patients in South Africa: An eight year review of SANBS mobile therapeutic apheresis service, 2013-2020.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2021
Same author

Analysis of extracorporeal photopheresis within the frame of the WAA register.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2021
Same author

Evaluation of health and quality of life in apheresis patients - data from the WAA register.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2019
Same author

HBsAg loss after peginterferon-nucleotide combination treatment in chronic hepatitis B patients: 5 years of follow-up.

Journal of viral hepatitis·2017
Same journal

Dynamic myeloid suppressor states in cancer and inflammation and their therapeutic potential.

Current opinion in hematology·2026
Same journal

Factor XIa inhibition for the prevention of thrombosis: mechanism, clinical trial signals, and indication-specific positioning.

Current opinion in hematology·2026
Same journal

Nutrition as a regulator of hematopoietic stem cell biology and transplantation.

Current opinion in hematology·2026
Same journal

From biomimicry to clinical actionability: rethinking high-shear thrombosis as a mechanobiological system.

Current opinion in hematology·2026
Same journal

Bidirectional relationship between metabolic and thrombotic disease mechanisms.

Current opinion in hematology·2026
Same journal

The dual role of the brain-derived neurotrophic factor as a regulator of hemostasis and thrombotic risk.

Current opinion in hematology·2026
See all related articles

Blood transfusions can transmit infectious agents like HIV, HBV, and HCV. Current safety measures significantly reduce risk, but future methods like nucleic acid testing and photochemical decontamination promise even greater safety for blood products.

Area of Science:

  • Transfusion Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Blood products can transmit various infectious agents, including viruses, bacteria, and parasites.
  • Key transfusion-transmitted viruses include human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-cell lymphotropic virus (HTLV).
  • Other viral agents like cytomegalovirus and parvovirus B19 can also be transmitted via blood products.

Purpose of the Study:

  • To review methods for preventing the transmission of blood-borne infectious agents.
  • To assess the current residual risk of transfusion-transmitted infections.
  • To discuss future strategies for enhancing blood product safety.

Main Methods:

  • Review of existing literature on blood product safety and infectious agent transmission.

Related Experiment Videos

  • Analysis of current screening and viral inactivation techniques for donated blood.
  • Evaluation of emerging technologies for pathogen detection and decontamination.

    • Main Results:

    • Current precautionary measures, including donor selection and blood testing, have substantially reduced transfusion-transmitted infections.
    • The estimated risk for infection from screened blood components in Europe and the US is low, ranging from 1 in 50,000 to 1.6 million for HBV, HCV, and HIV.
    • Ongoing advancements aim to further minimize residual risks.

    Conclusions:

    • Despite significant progress, the transmission of infectious agents via blood products remains a concern.
    • Enhanced screening methods like nucleic acid amplification techniques (NAATs) can improve safety.
    • Photochemical decontamination offers a promising approach for further securing cellular blood components.