Hypopigmentation and Desquamation as Dermatologic Reactions to Aralen

A 55-year-old white male while on Aralen(R) (chloroquine phosphate, Sanofi-Winthrop) developed desquamation and hypopigmentation of both hands. Dermatologic manifestations of chloroquine side effects are uncommon, and the appearance of desquamation has not been reported. There were no other accountable factors that appeared to contribute to this phenomenon.