[2 clinico-genetic types of primary congenital glaucomas in Slovakia]

The authors present the results of a 20-year follow-up of a group of 125 patients with primary congenital glaucoma. Based on 10 fundamentally different indicators they provided evidence of two clinical forms of primary congenital glaucoma depending on the ethnic origin and type of heredity. In Slovakia is found: a/autosomal recessive hereditary primary congenital glaucoma in the gypsy population with an identified gene locus GLC3A with a different clinical picture, severe course and unfavourable therapeutic results; b/multifactorial primary congenital glaucoma in the remaining population of Slovakia with different clinical parameters, a milder course and favourable therapeutic results.