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Postradiation morphea

M H Gollob1, J G Dekoven, M J Bell

  • 1Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.

The Journal of Rheumatology
|November 18, 1998
PubMed
Summary
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Morphea, a skin condition, can occur after breast cancer radiotherapy. Early diagnosis and topical steroid treatment led to significant improvement in a patient with post-radiation morphea.

Area of Science:

  • Dermatology
  • Oncology
  • Radiotherapy

Background:

  • Breast cancer treatment, including lumpectomy and radiotherapy, can have rare cutaneous side effects.
  • Morphea, a localized scleroderma, is an infrequently recognized complication following radiation therapy.

Observation:

  • A 54-year-old woman developed morphea on the right breast after undergoing radiotherapy for infiltrating lobular carcinoma.
  • Skin biopsy confirmed the histological diagnosis of morphea.

Findings:

  • Treatment with topical and intralesional steroids resulted in marked improvement of the morphea.
  • Early diagnosis is crucial for effective management.

Implications:

  • This case highlights morphea as a potential, though uncommon, sequela of breast radiotherapy.

Related Experiment Videos

  • Prompt recognition and localized steroid therapy can effectively manage radiation-induced morphea.