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Related Experiment Videos

A trial to detect behavioral changes by swimming stress

M Imaizumi1, S Miyazaki, T Fushiki

  • 1Laboratory of Nutrition Chemistry, Graduate School of Agriculture, Kyoto University, Japan.

Methods and Findings in Experimental and Clinical Pharmacology
|November 20, 1998
PubMed
Summary

Forced swimming stress temporarily suppressed mouse behavior, with recovery influenced by opioidergic systems. This model aids in studying exercise-induced behavioral and psychological changes.

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Area of Science:

  • Neuroscience
  • Behavioral Science
  • Pharmacology

Background:

  • Forced swimming is a stressor used to induce behavioral changes.
  • Understanding the neurobiological mechanisms underlying stress recovery is crucial.

Purpose of the Study:

  • To investigate behavioral alterations in mice following forced swimming stress.
  • To explore the role of opioidergic systems in the recovery of locomotor activity.

Main Methods:

  • Mice underwent a forced swimming stress test in a streaming pool.
  • Behavioral changes were assessed using a light/dark test.
  • The effect of naloxone on recovery was examined.

Main Results:

  • Locomotion and rearing were suppressed immediately after swimming, with gradual recovery.

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  • Shuttle crossing was suppressed, but time in the light zone was unaffected.
  • Naloxone administration hindered locomotor activity recovery post-swimming.

    • Conclusions:

    • The forced swimming model is effective for studying exercise-induced behavioral and psychological changes.
    • Opioidergic systems appear to play a role in the recovery of spontaneous locomotor activity after stress.