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Properties of retinoids. Structure, handling, and preparation
1Department of Biochemistry and Biophysics, Iowa State University, Ames 50011, USA. abarua@iastate.edu
Molecular Biotechnology
|November 20, 1998
Abstract:
Retinoids are unstable compounds being readily oxidized and/or isomerized to altered compounds, especially in the presence of oxidants including air, light, and excessive heat. They are labile toward strong acids and solvents that have dissolved oxygen or peroxides. In this review, procedures for handling and storage of retinoids and biological samples containing them have been described. The physical and chemical properties of retinoids have been reported. Simplified procedures for derivatizations and purification, and methods for quantitation of retinoids have been presented.