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Long-term parenteral nutrition

K Ladefoged, S Jarnum

    British Medical Journal
    |July 22, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Long-term parenteral nutrition (LTPN) at home is a viable treatment for patients with intestinal failure, offering an acceptable quality of life despite potential complications. This study highlights its practicality for managing conditions like Crohn's disease and short-bowel syndrome.

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    Area of Science:

    • Gastroenterology
    • Clinical Nutrition
    • Home Healthcare

    Background:

    • Long-term parenteral nutrition (LTPN) is essential for patients with intestinal failure.
    • Indications include Crohn's disease, intestinal fistulas, and short-bowel syndrome.
    • Home-based LTPN offers a potential solution for long-term management.

    Purpose of the Study:

    • To evaluate the feasibility and outcomes of home-based LTPN.
    • To identify complications associated with LTPN.
    • To assess the quality of life for patients receiving LTPN at home.

    Main Methods:

    • Retrospective analysis of 19 patients receiving LTPN for 6-63 months.
    • Data collection on indications, catheter types, complications, and quality of life.

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  • Review of complications including pneumothorax, thrombosis, sepsis, and liver function disturbances.

    • Main Results:

    • Common complications included pneumothorax, central vein thrombosis, and catheter sepsis.
    • Five patient deaths occurred, with two potentially related to LTPN.
    • Eight of 14 survivors still required LTPN, but six reported acceptable quality of life.

    Conclusions:

    • Home-based LTPN is practicable for selected patients with intestinal failure.
    • Despite complications, LTPN can support an acceptable quality of life.
    • Careful management is crucial to mitigate risks associated with LTPN.