Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Genetics and human reproduction

¹Wellcome/CRC Institute, Cambridge, UK. a.mclaren@welc.cam.ac.uk

Trends in Genetics : TIG

|November 20, 1998

Summary

Assisted reproduction practitioners aim to ensure healthy babies by addressing genetic disorders. They must tackle the challenge of inherited diseases and chromosomal abnormalities for couples seeking fertility treatments like in vitro fertilization (IVF).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Optimising same day discharge hemithyroidectomy: defining outcomes, unplanned admissions and patient experience.

Annals of the Royal College of Surgeons of England·2025

Same author

Development of a novel Bluetooth Low Energy device for proximity and location monitoring in grazing sheep.

Animal : an international journal of animal bioscience·2024

Same author

Genome-wide association studies of parasite resistance, productivity and immunology traits in Scottish Blackface sheep.

Animal : an international journal of animal bioscience·2024

Same author

Thyroid lobectomy for low-risk thyroid cancers.

Annals of the Royal College of Surgeons of England·2022

Same author

Metastatic seminoma with isolated gastric metastases: a case report.

Scottish medical journal·2019

Same author

New mastitis phenotypes suitable for genomic selection in meat sheep and their genetic relationships with udder conformation and lamb live weights.

Animal : an international journal of animal bioscience·2018

Area of Science:

Reproductive Medicine
Medical Genetics
Human Embryology

Background:

Most individuals desire children, with a strong preference for healthy offspring.
Assisted reproductive technologies (ART) like in vitro fertilization (IVF) and donor insemination (DI) assist infertile couples.
A significant challenge in ART is preventing the transmission of inherited diseases and chromosomal abnormalities.

Purpose of the Study:

To explore the responsibilities of practitioners in ensuring the health of babies conceived through assisted reproduction.
To identify strategies for managing the risks of inherited diseases and chromosomal malfunctions in ART.
To address the challenge of approximately 4000 known inherited diseases.

Main Methods:

This abstract outlines a conceptual challenge rather than detailing specific experimental methods.
It frames a discussion on the ethical and practical considerations in genetic screening and counseling within ART.
The focus is on the responsibility of clinicians in the context of known genetic and chromosomal risks.

Main Results:

The abstract does not present empirical results but highlights a critical area of concern in reproductive medicine.
It emphasizes the need for effective methods to screen for and manage genetic and chromosomal conditions.
The inherent complexity of over 4000 known inherited diseases is acknowledged as a significant hurdle.

Conclusions:

Practitioners in assisted reproduction have a profound responsibility to minimize the risk of genetic and chromosomal disorders in offspring.
Proactive strategies are essential to ensure the health of children born via IVF and other ART.
Addressing the vast spectrum of inherited diseases requires ongoing advancements in genetic diagnostics and counseling.

Related Experiment Videos