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Sexing of human and other primate DNA
1Zoologisches Institut, Universität München, Germany.
Biological Chemistry
|November 20, 1998
Abstract:
We present a rapid and simple method for the sexing of human and other primate DNA. Homologous introns from the X- and Y-linked zinc finger protein genes (ZFX and ZFY) are PCR amplified with one primer pair. An Alu element insertion in the ZFX intron results in a size difference in the amplicons which is resolved by agarose gel electrophoresis.