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Characterization of fibrous retrocorneal membrane by confocal microscopy
A G Chiou1, C Chang, S C Kaufman
1Louisiana State University Eye Center, New Orleans 70112-2234, USA.
Purpose:
To study the appearance of a fibrous retrocorneal membrane as seen by confocal microscopy.
Methods:
A 67-year-old white woman with a history of multiple ocular surgeries, including repeated penetrating keratoplasties for aphakic bullous keratopathy, developed a retrocorneal membrane in the right eye. The membrane was first noticed 3 years after the last corneal transplant and remained stable subsequently. The patient was examined by in vivo white light tandem-scanning confocal microscopy.
Results:
At the level of the retrocorneal membrane, confocal microscopy disclosed the presence of a hyperreflective fibrous-appearing layer. Normal endothelial cells could not be found. Anterior to the hyperreflective layer, activated keratocytes were identified.
Conclusion:
Confocal microscopy may allow noninvasive diagnosis of fibrous retrocorneal membrane. Additionally, our data suggest that the posterior keratocytes might play a role in the production and deposition of fibrous tissue.