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Intravascular infection with Lactobacillus paracasei

S Sturdee1, R Bainton, M Barnham

  • 1Department of Medicine, Harrogate District Hospital, Harrogate, North Yorkshire, U.K.

The Journal of Infection
|November 24, 1998
PubMed
Summary

A rare intravascular infection caused by Lactobacillus paracasei led to a life-threatening mycotic aneurysm rupture. Prompt splenectomy and antibiotics successfully treated this severe Lactobacillus infection.

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Area of Science:

  • Infectious Diseases
  • Vascular Surgery
  • Microbiology

Background:

  • Intravascular infections pose significant clinical challenges, often requiring complex management strategies.
  • Mycotic aneurysms, infections of arterial walls, can lead to catastrophic complications if not promptly addressed.

Observation:

  • A patient presented with a subacute yet life-threatening intravascular infection attributed to Lactobacillus paracasei.
  • The infection resulted in intrasplenic mycotic aneurysm rupture, causing significant hematoma, early abscess formation, and peritoneal bleeding.

Findings:

  • Surgical intervention via splenectomy was crucial for controlling the infection and its complications.
  • A prolonged course of ampicillin and gentamicin demonstrated efficacy in eradicating the Lactobacillus paracasei infection.

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Implications:

  • This case highlights the potential severity of Lactobacillus intravascular infections and the importance of early diagnosis and intervention.
  • Effective treatment necessitates a combination of surgical management and targeted antimicrobial therapy, emphasizing the role of specific antibiotic combinations.