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Sorption of non-narcotic analgetic drugs of medicinal charcoal
1Department of Inorganic and Analytical Chemistry, Karol Marcinkowski University of Medical Sciences, Poznań, Poland.
Acta Poloniae Pharmaceutica
|November 20, 1998
Abstract:
Adsorption of four 5-pyrazolone derivatives and two carboxylic acids from aqueous solutions was studied. Partition coefficients for the analyzed drugs were calculated. Good corelation between log(k1, k2) (Langmuir constants) and log (octanol-water partition coefficient) of the drugs were found. The higher log(k1k2) value the higher solubility of the non-narcotic and analgetic drugs.