Idiopathic pulmonary fibrosis and cyclosporine: a lesson from single-lung transplantation

Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and therapeutic options are limited with a 5-year survival of less than 50%. This report includes a case of histologically confirmed IPF in a patient whose native lung showed objective improvement as measured by high-resolution CT while he was receiving cyclosporine-based immunosuppressive therapy after single-lung transplantation.