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Radiation therapy for tracheobronchial amyloidosis
J A Kurrus1, J K Hayes, J R Hoidal
1Medicine Service, Veterans Affairs Medical Center, Salt Lake City, UT, USA.
Chest
|November 21, 1998
Summary
Localized tracheobronchial amyloidosis can cause airway obstruction. External beam radiation therapy showed a positive response and should be considered for localized cases.
Area of Science:
- Pulmonology
- Oncology
Background:
- Tracheobronchial amyloidosis is a rare condition.
- Localized disease can lead to significant airway obstruction.
Observation:
- A 67-year-old man with localized amyloidosis of the distal trachea and right airways presented with right middle lobe collapse.
Findings:
- Bronchoscopic interventions (Nd:YAG laser, dilation, stenting) provided temporary relief.
- External beam radiation therapy demonstrated a measurable local response in disease progression.
Implications:
- External beam radiation therapy is a potential treatment option for localized tracheobronchial amyloidosis.
- Radiation therapy may help manage airway obstruction caused by this rare condition.