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Gastric involvement in AIDS associated cryptosporidiosis
P Rossi1, F Rivasi, M Codeluppi
1Laboratory of Parasitology, Istituto Superiore di Sanità, Rome, Italy.
Background:
Cryptosporidiosis has been shown to be a common cause of diarrhoea in both immunocompetent and immunosuppressed individuals. There are very few data on the distribution of Cryptosporidium parvum along the gastrointestinal tract.
Aims:
To evaluate the location of Cryptosporidium parasites in the digestive tract of patients with AIDS.
Methods:
Gastrointestinal localisation of C parvum was studied in 71 patients with AIDS who underwent upper and/or lower endoscopy with biopsy for chronic diarrhoeal illness and/or other gastrointestinal disorders of unexplained origin.
Results:
Twenty four individuals (33.8%) were positive for C parvum, of which 16 (88.9%) had parasites in the gastric epithelium. Most patients with gastric localisation of C parvum did not show specific symptoms indicating the presence of this parasite in the stomach.
Conclusions:
Gastric involvement in AIDS related cryptosporidiosis is more frequent than expected, but no clear correlation between gastric location and related clinical and pathological features was observed.
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