Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode

C Veraart1, C Raftopoulos, J T Mortimer

  • 1Neural Rehabilitation Engineering Laboratory, Université Catholique de Louvain, Avenue Hippocrate, 54, UCL-54.46 B-1200, Brussels, Belgium. veraart@gren.ucl.ac.be

Brain Research
|November 24, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Invited review: Global census on the development and implementation of direct genetic selection for enteric methane emissions in dairy cattle.

Journal of dairy science·2026
Same author

Surgical Treatment of Cushing's Disease: The Lessons Learned.

Advances and technical standards in neurosurgery·2025
Same author

Combining short-term breath measurements to develop methane prediction equations from cow milk mid-infrared spectra.

Animal : an international journal of animal bioscience·2024
Same author

How to reduce the complication rate of multiple burr holes surgery in moyamoya angiopathy.

Acta neurochirurgica·2023
Same author

Prediction of key milk biomarkers in dairy cows through milk mid-infrared spectra and international collaborations.

Journal of dairy science·2023
Same author

Ectopic sphenoidal ACTH-secreting adenoma revealed by <sup>11</sup>C Methionine PET scan: case report.

BMC endocrine disorders·2023

Electrical stimulation of the optic nerve in a blind volunteer with retinitis pigmentosa generated visual sensations. This research shows promise for developing a visual prosthesis for blindness.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Ophthalmology

Background:

  • Retinitis pigmentosa causes progressive vision loss due to photoreceptor degeneration.
  • Current treatments for retinitis pigmentosa are limited, necessitating novel approaches for vision restoration.
  • Optic nerve stimulation offers a potential pathway for bypassing damaged retinal pathways.

Observation:

  • A chronically implanted, self-sizing spiral cuff electrode was placed around the optic nerve of a blind volunteer.
  • Electrical stimulation parameters were systematically varied to assess responses.
  • The volunteer reported experiencing visual sensations in response to stimulation.

Findings:

  • Stimulation of the optic nerve elicited localized visual sensations.

Related Experiment Videos

  • These sensations were broadly distributed across the visual field.
  • The characteristics of the visual sensations varied with different electrical stimulation conditions.

    • Implications:

    • This study demonstrates the feasibility of using optic nerve stimulation for visual prostheses.
    • It suggests a potential strategy for restoring vision in individuals with retinitis pigmentosa and intact retinal ganglion cells.
    • Further research could optimize electrode design and stimulation protocols for improved visual perception.