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Related Experiment Videos

Sterile connector

F J Tenczar

    Transfusion
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    A novel sterile connector design enables safe fluid transfer through contaminated areas. Two methods, mechanical or thermal, ensure sterility for applications from parenteral therapy to complex biological component processing.

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    Area of Science:

    • Biomedical Engineering
    • Sterilization Technologies
    • Medical Device Design

    Background:

    • Sterile connectors are crucial for medical fluid transfer.
    • Existing connectors may not adequately prevent contamination during connection.
    • Need for robust sterile connection methods in diverse medical applications.

    Purpose of the Study:

    • To design a sterile connector system for joining supply sources to delivery locations through contaminated environments.
    • To develop methods for maintaining sterility during the connection process.
    • To offer adaptable solutions for various medical fluid and component transfer needs.

    Main Methods:

    • Two fabrication approaches were explored: mechanical and thermal.
    • Mechanical method involves modified protective covers with adhesive antimicrobiologic agents for barrier penetration.

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  • Thermal method uses a nichrome wire (approx. 288 C) to fuse, sterilize, and penetrate plastic barrier membranes.

    • Main Results:

    • The mechanical approach offers an economical solution for parenteral fluid therapy.
    • The thermal (nichrome wire) method is suitable for complex processing, such as with frozen erythrocytes.
    • Both methods ensure the exclusion and sterilization of the connection environment before internal conduit coupling.

    Conclusions:

    • A versatile sterile connector system can be fabricated using either mechanical or thermal penetration techniques.
    • The choice of method depends on the specific application's complexity and storage requirements.
    • This design facilitates safe and sterile connections in challenging environments, enhancing medical fluid and component transfer safety.