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Sequelae associated with cerebral candidiasis in two premature infants
1Department of Newborn and Developmental Pediatrics, Women's College Hospital, Toronto, Ontario, Canada.
Acta Paediatrica (Oslo, Norway : 1992)
|November 24, 1998
Summary
Two premature infants survived cerebral candidiasis, a serious fungal infection of the brain. However, both experienced significant long-term developmental disabilities following treatment.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
- Infectious Diseases
Background:
- Cerebral candidiasis is a rare but severe opportunistic infection affecting premature infants.
- Early diagnosis and treatment are crucial for improving outcomes in neonatal fungal infections.
Observation:
- This report details two cases of premature neonates diagnosed with cerebral candidiasis.
- Both infants received treatment for the fungal brain infection.
Findings:
- Both infants survived the acute phase of cerebral candidiasis.
- Long-term follow-up revealed significant neurodevelopmental handicaps in both surviving infants.
Implications:
- Cerebral candidiasis survivors face a high risk of long-term neurological sequelae.
- This highlights the need for comprehensive, long-term neurodevelopmental monitoring in premature infants treated for invasive fungal infections.