Related Experiment Videos
Sialic acid-dependent recognition of laminin by Penicillium marneffei conidia
A J Hamilton1, L Jeavons, S Youngchim
1Dunhill Dermatology Unit, St John's Institute of Dermatology, Guy's Hospital, London, United Kingdom. a.hamilton@umds.ac.uk
Infection and Immunity
|November 24, 1998
Abstract:
Immunofluorescence microscopy demonstrated that laminin bound to the surface of Penicillium marneffei conidia. Attachment of P. marneffei conidia in an adherence assay was inhibited by soluble laminin and anti-laminin antibody. N-Acetylneuraminic acid abolished adherence, indicating an interaction mediated by a sialic acid-specific lectin.