Related Experiment Videos
High-performance capillary electrophoresis determination of pyrithione in antidandruff preparations and shampoos
E M Peña-Méndez1, J Havel, J Malecek
1Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Tenerife, Spain.
Journal of Capillary Electrophoresis
|November 25, 1998
Abstract:
A simple and rapid high-performance capillary electrophoresis (HPCE) method for the determination of 2-mercaptopyridine-1-oxide (pyrithione) was developed. After addition of ethylenediaminetetraacetic acid (EDTA), pyrithione was determined in the form of the free anion using 50 mM borate (pH 9.2) as background electrolyte and was detected at 244 nm with a limit of detection (LOD) of 0.636 ppm (S/N = 3). The method was used to check the purity of pyrithione preparations and for the determination of pyrithione in shampoo.