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Related Experiment Videos

Late recall urticaria

M Karaayvaz1, N Ozangüç

  • 1Gülhane Military Medical Academy, Department of Allergic Diseases, Ankara, Turkey.

Journal of Investigational Allergology & Clinical Immunology
|November 25, 1998
PubMed
Summary
This summary is machine-generated.

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Delayed recall urticaria can occur weeks after immunotherapy injections. An 11-year-old boy experienced persistent urticarial lesions 48-72 hours post-injection, even after treatment frequency decreased.

Area of Science:

  • Allergy and Immunology
  • Dermatology
  • Clinical Medicine

Background:

  • Immunotherapy for allergic rhinitis involves allergen extracts.
  • Recall urticaria typically manifests within an hour of exposure.
  • Pollen immunotherapy uses extracts like Phleum pratense and Festuca elatior.

Observation:

  • An 11-year-old boy developed urticarial lesions 48-72 hours after pollen immunotherapy.
  • Lesions appeared on the contralateral arm, at previous injection sites.
  • Reactions persisted throughout immunotherapy, even with reduced frequency.

Findings:

  • Delayed hypersensitivity reaction presenting as recall urticaria.
  • Urticarial lesions appeared 48-72 hours post-injection, deviating from the typical immediate reaction.

Related Experiment Videos

  • The reaction pattern evolved, with lesions appearing every 2-3 injections over time.
  • Implications:

    • Highlights a delayed presentation of recall urticaria in immunotherapy.
    • Suggests the need to consider delayed hypersensitivity in immunotherapy adverse events.
    • Informs clinical management of unexpected cutaneous reactions during allergen immunotherapy.